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Latest Innovations

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Project MicroRNA-218: A Novel Therapeutic Agent for Motoneuron Diseases and Use of Its Promoter for Targeted Gene Therapy

Investigators at the Salk Institute have demonstrated that microRNA-218 (miR-218) is abundantly and selectively expressed

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Primary: The Salk Institute
Date posted: Dec 18, 2015
Project Sonogenetics – a novel, non-invasive and selective method to examine and manipulate cellular activity and function

Salk scientists have developed a new way to selectively activate brain, heart, muscle and other cells

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Primary: The Salk Institute
Date posted: Sep 22, 2015
Project CREKA-SPIO Nanoparticles- Superior MRI Tracers for Tumor Imaging

Primary: Sanford Burnham Prebys Medical Discovery Institute
Date posted: Jun 17, 2015
Project Novel Compounds with Neuroprotective and Anti-inflammatory Properties

Salk investigators have developed synthetic derivatives of the naturally occurring flavonoid fisetin (3,7,3',4' tetrahydroxyflavone). These derivatives

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Primary: The Salk Institute
Date posted: May 19, 2015
Project VAS1 Mutant Coordinates Auxin and Ethylene Biosynthesis in Shade Avoidance Responses

Uncoupling Linked Auxin and Ethylene Biosynthetic Pathways in Plants; Increasing Crop Yields and Biomass

Primary: The Salk Institute
Date posted: Jan 7, 2015
Project Understanding Neural Networks: Identifying Monosynaptic Connections

INVENTION: Ed Callaway has identified a novel method for understanding neural networks by using a synaptic tracer

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Primary: The Salk Institute
Date posted: Jan 6, 2015
Project Transgenic Mice Expressing a Human SXR Receptor Polypeptide (Alb-hSXR-Tg and FABP-hSXR-Tg mice available)

INVENTION: SXR is a nuclear receptor whose primary function is to sense the presence of foreign

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Primary: The Salk Institute
Date posted: Jan 6, 2015
Project TLX null; b-gal knock-in mice

INVENTION: Orphan nuclear receptor TLX is expressed in adult mammalian brains and critical in maintaining

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Primary: The Salk Institute
Date posted: Jan 6, 2015
Project Retinoid X Receptor (RXR) alpha-Deficient Animals and Cell Lines

APPLICATIONS: These animals have a targeted loss-of-function mutation in the RXR alpha gene in the mouse

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Primary: The Salk Institute
Date posted: Jan 6, 2015
Project Regulation of EIN2 Protein to Promote Fruit Ripening and Increase Plant Biomass

INVENTION: EIN2 is an integral membrane protein with a short half-life that undergoes rapid proteasome-mediated protein

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Primary: The Salk Institute
Date posted: Jan 6, 2015